Should In Vitro Fertilization Be Regulated?

Although I definitely do not want eight babies and have no desire to be Angelina Jolie (I’m a Clooney kind of gal, not a Pitt one), I still want to understand the position of Nadya Suleman and other women who have opted to have multiple births. What might lead a mother to even make twins or quadruplets—or more—possible? And who is responsible when in vitro fertilization produces more babies than intended?

Although fertility technology has been around for decades, the ethical conundrums and ambiguous regulations leave much to be figured out.

How Did We Get Here?
It’s been thirty-one years since the first test tube baby was born in England. Little Louise Brown was front-page news. Her birth was the thing of science fiction. It was the first time an embryo had been fertilized outside a mother’s womb, transferred back to the mother, and then produced a healthy baby—one who is still very much alive and who had her own child in 2008. Since 1978, more than three million babies have been born using the technology. Gradually, the term test tube baby gave way to the Latin variation in vitro, or IVF. No matter its name, the procedure is no bed of roses.

It all starts with shots. Plenty of them. During her period, a woman starts getting injections of a fertility medication for a course of about ten days. After enough follicles have developed in the ovaries, between ten to thirty eggs are retrieved using an ultrasound-guided needle that pierces the vaginal wall. Next, the woman can breathe easy as the work moves to the lab, where the eggs are incubated with sperm. It takes between two to five days for embryos to develop, after which the best ones are selected (yes, we judge each other even at this earliest of stages) and transplanted through a plastic catheter through the vagina and cervix and into the uterus.

No bed of roses, as I said. And yet there are more than 60,000 IVF cycles performed in the United States every year, at a cost of up to $10,000 per cycle—if you’re American, that is. In many European countries, as well as Canada, nationalized health plans cover IVF. It’s no coincidence that these countries also regulate how many embryos can be implanted in the last stage of the in vitro process. In the United Kingdom, for example, only two embryos can be transferred.

Lax Control, Lots of Babies
In the U.S. there are guidelines from the American Society for Reproductive Medicine (ASRM) regarding the number of embryos that can be transferred. For women under thirty-five, it’s two; for women over age forty, no more than five transfers should be attempted. These, however, are guidelines, not regulations, and a woman can ask her doctor to do more. Many doctors comply: the guidelines are so widely disregarded that the Centers for Disease Control and Prevention report that only 20 percent of clinics follow the ASRM guidelines.

Obviously, IVF pregnancies and healthy births are significantly more common now than in the years just following Louise Brown’s arrival. According to the Canadian Press, 36 percent of embryonic implants result in pregnancies—a decent number but not high enough for people paying a significant amount of money. The discrepancy between the cost of IVF and the statistical probability of a successful birth is what leads people to ignore the guidelines.

More Embryos, More Cost and Risk
Does it matter? Yes, say many ethicists, parents who have experienced IVF, and medical experts. As photographs of the octuplets born in California this January show, multiples often result in premature births and various medical complications, even in less sensational cases. The European Society of Human Reproduction and Embryology Research has reported that triplet pregnancies cost more than eight times as much as singleton pregnancies and twin pregnancies cost more than three times as much. The current trend in the U.S. for multiple transfers, which has resulted in Americans leading the world in the births of multiples, has become an ethical issue.

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08.09.2009
Faith
jollyegirl, I (and many women I know) have found Clomid to be a worse medication to take from an emotional side-effect standpoint than the stimulation medications used in IVF. It is the nastiest medication I have ever taken (and I have done 9 IVF cycles) As for regulating the number of embryos that may be transferred during an IVF cycle to an absolute limit for any patient at any age, I very much disagree. Many patients are actually very well educated and informed on the process of IVF, and are prepared for the ethical choices they might face should the extrodinary occur (such as 3 embryos split into 6). Yes, it can occur sometimes, but not all that often. There are times when transferring more than 3 embryos is appropriate and involves very little risk of multiples, let alone high order multiples. The way I see it "they" don't pump drugs into your system, you CHOOSE to take medications to hopefully conceive, IF that is a choice you are willing to make to have a child.
08.09.2009
Faith
Canada’s nationalized health care system does NOT cover IVF throughout Canada. Each province determines specific treatments and procedures that are covered under the health care plan, and currently only ONE province in Canada covers IVF, and then only in some very limited cases of infertility (The province of Ontario covers IVF for women with bilateral tube blockage only-a minority of cases). Currently one more province has plans to begin offering funded IVF cycles this year (Quebec). In Canada, there is no law/regulation regarding how many embryos can be transferred during an IVF cycle, there are professional guidelines only. The guidelines work well to provide a standard of practice in average cases, while still allowing doctors the ability to treat individual patient cases on a case by case basis. Most patients pay out of pocket for the needed treatment.
04.28.2009
Grace Thomas
Nematoad, you're very rude. - I don't agree with the Octomom's decision and I worry greatly about the welfare of her children. I do find it interesting that collectively we seem to glorify some large families (the Duggers, Jon and Kate plus 8) but are offended greatly by Octomom. Even in the best of circumstances, there are limits to how many children a family can take care of.
04.07.2009
Nematoad
such a bunch of Elite, neo Fascist pigs that we have become in this country! You can't tell us how many children is too many! We live in a free country, in which we can have as many children as we can birth. I am all for maximum growth rate. The more the merrier!
04.05.2009
Miranda
I think it is an outrageous obtusive, non-enough knowledge or expertise to be playing with. At least by the means of the ouctuplet woman. That was absolutlely disgusting! Regulations and ethical suggestions have to put into play. I am one of the ones who is paying for this doctor freak!
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